CD117 expression on blast cells in acute myeloid leukemia.
نویسندگان
چکیده
منابع مشابه
PROGNOSTIC VALUE OF MYELOID ANTIGEN EXPRESSION IN ACUTE LYMPHOBLASTIC LEUKEMIA
Expression of cell surface molecules associated with lymphoid and myeloid lineage differentiation on the blasts of 53 patients with acute lymphoblastic leukemia (ALL) was investigated. 1.9% of cases were only HLA"7DR+ 7.6% were HLA-DR+, CDI9+ 22.6% were HLA-DR+, CDI9+, CDI0+ 30.2% were HLADR+, CDI9+, CDlO±, CD20+ and 37.7% were HLA-DR±, CD7+, CD5±. Aberrant expression of one or more myeloi...
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NK cells expressing TIM-3 show a marked increase in IFNγ production in response to acute myeloid leukemia (AML) blast cells that endogenously express Gal-9. Herein, we demonstrate that NK cell-mediated production of IFNγ, induced by TIM-3/Gal-9 interaction and released in bone marrow microenvironment, is responsible for IDO1 expression in AML blasts. IDO1-expressing AML blasts consequently down...
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DOI: 10.1590/S1679-45082016AI3516 Acute myeloid leukemia (AML) results from accumulation of abnormal blasts in the bone marrow, interfering with hematopoiesis.(1) Multiparametric flow cytometry is an important and well-known tool for AML diagnosis and for monitoring of minimal residual disease.(2) However, this technique is still poorly explored to elucidate clonal evolution of the leukemia. We...
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ژورنال
عنوان ژورنال: Medicni perspektivi (Medical perspectives)
سال: 2015
ISSN: 2307-0404
DOI: 10.26641/2307-0404.2015.3.53688